Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725382 | 0.73 | LMNA (0.35) | LMNAMAPT | |
| SCHEMBL8308065 | 0.72 | LMNA (0.34) | LMNAMAPT | |
| SCHEMBL13506273 | 0.71 | MAOB (0.39) | MAOBMAOALMNAMAPTDYRK1A | |
| SCHEMBL2156974 | 0.71 | ALDH1A1 (0.36) | MAOBMAOALMNAMAPTDYRK1A | |
| SCHEMBL8615385 | 0.69 | MAOB (0.34) | MAOBMAOALMNAMAPTGRM5 | |
| SCHEMBL769591 | 0.65 | MAP3K14 (0.42) | MAOBMAOALMNAMAPTKDM4E | |
| SCHEMBL27203819 | 0.65 | PTGS2 (0.39) | MAOBMAOALMNAMAPTDYRK1A | |
| SCHEMBL56658 | 0.65 | MAOB (0.46) | MAOBMAOALMNAMAPTDYRK1A | |
| SCHEMBL20480683 | 0.64 | MAPT (0.61) | LMNAMAPTKDM4E | |
| SCHEMBL8219507 | 0.64 | MAOA (0.35) | MAOBMAOALMNAMAPTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629623-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5587484-A | HALOGENATION; OXIDATION; SULFONATION; HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5480858-A | HERBICIDES; LOW DOSAGE; CORN, BARLEY, WHEAT | IDEMITSU KOSAN CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5468722-A | Herbicides for corn, wheat, barley | IDEMITSU KOSAN CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0629623-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-12-21 | — | — | EP | disclosed |