SCHEMBL8307321

SCHEMBL8307321

Cn1cnc(-n2nn[nH]c2=O)c1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.31
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
MTOR P42345 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686617 0.67 RAB9A (0.45)
SCHEMBL8304144 0.67
SCHEMBL8302279 0.66 LPO (0.34)
SCHEMBL8307323 0.66 PRMT5 (0.32)
SCHEMBL8306758 0.66 PRMT5 (0.33)
SCHEMBL8303900 0.64 MAPT (0.36)
SCHEMBL8308735 0.64 PRMT5 (0.33)
SCHEMBL8308632 0.64
SCHEMBL8306756 0.64 PNP (0.39)
SCHEMBL8306630 0.64 LMNA (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
EP-0906296-A1 PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS WARNER-LAMBERT COMPANY LLC (US) 1999-04-07 EP disclosed
WO-1997048687-A1 PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS WARNER-LAMBERT COMPANY (US) 1997-12-24 WO disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed