Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295676 | 0.83 | MAPT (0.53) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16655546 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30989211 | 0.80 | TDP1 (0.62) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2929031 | 0.80 | TDP1 (0.62) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12798874 | 0.80 | TDP1 (0.62) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8733637 | 0.80 | XDH (0.58) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL9511426 | 0.80 | VCAM1 (0.51) | TDP1ALDH1A1POLBCYP3A4HTT | |
| SCHEMBL11079242 | 0.79 | TDP1 (0.60) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31423774 | 0.79 | TDP1 (0.60) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11789708 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576251-B1 | Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment | SUNTORY LTD (JP) | 1999-11-24 | — | — | EP | claimed |
| EP-0960103-A1 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5948797-A | ANTITUMOR AGENT | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998031673-A9 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | — | 1998-12-10 | — | — | WO | disclosed |
| US-5807874-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1998031673-A1 | TERBENZIMIDAZOLES USEFUL FOR MEDICAL THERAPY (TOPOISOMERASE INHIBITORS) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5770617-A | Terbenzimidazoles useful as antifungal agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5767142-A | INHIBITION OF MAMMALIAN TUMOR CELL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0839140-A1 | TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1996036612-A1 | TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1996-11-21 | — | — | WO | disclosed |
| US-4060491-A | 5-ALKYL BENZOTRIAZOLE | MOBIL OIL CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |