Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8304376 | 0.99 | LMNA (0.40) | LMNAGAACNR2RAB9APTGS1 | |
| SCHEMBL8303462 | 0.83 | CES2 (0.38) | GAARAB9AKAT6A | |
| Bromide SCHEMBL10365922 | 0.82 | CES2 (0.37) | GAARAB9AKAT6A | |
| Bromide SCHEMBL8305746 | 0.82 | CES2 (0.37) | GAARAB9AKAT6A | |
| Bromide SCHEMBL8305743 | 0.82 | CES2 (0.37) | GAARAB9AKAT6A | |
| SCHEMBL8441148 | 0.81 | GABRP (0.48) | LMNACNR2RAB9APTGS1POLB | |
| Bromide SCHEMBL10367565 | 0.80 | GABRP (0.47) | LMNACNR2RAB9APTGS1POLB | |
| Hydrochloric Acid SCHEMBL8304040 | 0.80 | GABRP (0.47) | LMNACNR2RAB9APTGS1POLB | |
| SCHEMBL8306246 | 0.78 | CTSD (0.47) | LMNAHDAC1 | |
| SCHEMBL10909763 | 0.77 | RECQL (0.49) | LMNARAB9ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582182-B1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST MARION ROUSSEL INC (US) | 1999-10-20 | — | — | EP | claimed |