Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310455 | 0.91 | L3MBTL3 (0.33) | HTTKDM4EALDH1A1SMN1; SMN2L3MBTL3 | |
| SCHEMBL8310792 | 0.81 | L3MBTL3 (0.34) | HTTALDH1A1L3MBTL3L3MBTL1OPRM1 | |
| SCHEMBL6977637 | 0.79 | CHRM1 (0.30) | — | |
| SCHEMBL8574046 | 0.78 | ADRA1D (0.36) | HTTKDM4EALDH1A1SMN1; SMN2L3MBTL3 | |
| SCHEMBL8311208 | 0.76 | MAOB (0.32) | — | |
| SCHEMBL6977824 | 0.73 | DRD2 (0.39) | — | |
| SCHEMBL9698183 | 0.72 | OPRM1 (0.38) | ALDH1A1OPRM1OPRK1OPRD1GAA | |
| Hydrochloric Acid SCHEMBL8713715 | 0.71 | MEN1 (0.38) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL6976347 | 0.70 | CHRM1 (0.32) | — | |
| SCHEMBL6980124 | 0.70 | CHRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |