Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310455 | 0.85 | L3MBTL3 (0.33) | L3MBTL3L3MBTL1OPRM1OPRK1OPRL1 | |
| SCHEMBL8309484 | 0.81 | HTT (0.31) | L3MBTL3L3MBTL1OPRM1OPRK1OPRL1 | |
| SCHEMBL6984259 | 0.77 | MEN1 (0.35) | KMT2AACHEBACE1CHRM1 | |
| SCHEMBL6983514 | 0.77 | MEN1 (0.35) | KMT2AACHEBACE1CHRM1 | |
| SCHEMBL8574046 | 0.72 | ADRA1D (0.36) | L3MBTL3L3MBTL1OPRM1OPRK1OPRL1 | |
| SCHEMBL13597011 | 0.68 | L3MBTL1 (0.51) | L3MBTL3L3MBTL1OPRM1OPRK1OPRL1 | |
| SCHEMBL11371929 | 0.67 | ACHE (0.60) | L3MBTL3L3MBTL1KMT2AACHEBACE1 | |
| SCHEMBL659177 | 0.66 | MEN1 (0.36) | ALDH1A1GAAKMT2ALMNAMAOB | |
| SCHEMBL11374559 | 0.66 | ACHE (0.59) | OPRM1OPRK1OPRL1OPRD1GAA | |
| SCHEMBL9698183 | 0.65 | OPRM1 (0.38) | OPRM1OPRK1OPRD1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |