Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309484 | 0.91 | HTT (0.31) | L3MBTL3L3MBTL1DPP4OPRM1OPRK1 | |
| SCHEMBL8574046 | 0.87 | ADRA1D (0.36) | L3MBTL3L3MBTL1DPP4OPRM1OPRK1 | |
| SCHEMBL8310792 | 0.85 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1OPRM1OPRK1OPRL1 | |
| SCHEMBL8311208 | 0.85 | MAOB (0.32) | — | |
| SCHEMBL9698183 | 0.81 | OPRM1 (0.38) | OPRM1OPRK1OPRD1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL8713715 | 0.80 | MEN1 (0.38) | OPRM1OPRK1OPRD1CHRM2CHRM4 | |
| SCHEMBL6983077 | 0.79 | SOS1 (0.39) | SLC6A3MAPT | |
| Hydrochloric Acid SCHEMBL6983934 | 0.78 | SOS1 (0.39) | SLC6A3MAPT | |
| SCHEMBL6976347 | 0.77 | CHRM1 (0.32) | CHRM1 | |
| SCHEMBL6980124 | 0.77 | CHRM1 (0.32) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |