SCHEMBL8310906

SCHEMBL8310906

N#Cc1c(Br)cc(Br)c([N+](=O)[O-])c1C#N

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 5/20 0.39
GPR35 Q9HC97 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
TSHR P16473 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28440655 0.75 VCAM1 (0.39) VCAM1TDP1ALDH1A1MAPTTSHR
SCHEMBL31456573 0.75 VCAM1 (0.39) VCAM1TDP1ALDH1A1MAPTTSHR
SCHEMBL17041985 0.74 TRPV4 (0.37) VCAM1GPR35TDP1ALDH1A1MAPT
SCHEMBL18510270 0.73 ALDH1A1 (0.41) GPR35TDP1ALDH1A1MAPTTSHR
SCHEMBL8311529 0.72 XDH (0.42) VCAM1TDP1ALDH1A1MAPTTSHR
SCHEMBL17042143 0.72 ALDH1A1 (0.38) VCAM1GPR35TDP1ALDH1A1MAPT
SCHEMBL10879384 0.71 VCAM1 (0.47) VCAM1GPR35TDP1ALDH1A1MAPT
SCHEMBL17744436 0.71 TSHR (0.38) VCAM1GPR35ALDH1A1TSHRGRIN2D
SCHEMBL8310679 0.71 RAB9A (0.41) VCAM1GPR35TDP1ALDH1A1MAPT
SCHEMBL22445767 0.71 MEN1 (0.38) VCAM1TDP1ALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519423-B1 Phthalocyanine compounds and usage thereof MITSUI CHEMICALS INC (JP) 1999-03-03 EP disclosed
US-5695911-A CONTAINING PHTHALOCYANINE COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-12-09 US disclosed
US-5380842-A Color filters MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-01-10 US disclosed