Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207553 | 0.75 | GPR84 (0.41) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL7207549 | 0.72 | DRD4 (0.64) | KMT2A | |
| SCHEMBL6870381 | 0.70 | EGFR (0.38) | SMN1; SMN2 | |
| SCHEMBL29503015 | 0.66 | GPR84 (0.47) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL18702895 | 0.66 | GPR84 (0.47) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8984678 | 0.66 | MTNR1A (0.74) | — | |
| SCHEMBL1013714 | 0.65 | NR3C1 (0.40) | KMT2AMEN1MAPTRAB9AP2RX7 | |
| SCHEMBL8311758 | 0.65 | ALDH1A1 (0.38) | KMT2AMEN1PKMNPC1RAB9A | |
| SCHEMBL6382771 | 0.65 | MTNR1A (0.65) | PKMNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6565977 | 0.63 | TSHR (0.58) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923548-A1 | 4-AMINOETHOXY INDOLES AS DOPAMIN D2 AGONISTS AND AS 5HT 1A? LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008817-A1 | 4-AMINOETHOXY INDOLES AS DOPAMIN D2 AGONISTS AND AS 5HT1A LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |