Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | LIPC | P11150 | 3/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313399 | 0.85 | SCN9A (0.37) | CASRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6278357 | 0.84 | MMP8 (0.46) | RORCLIPGLIPCMMP3MMP9 | |
| SCHEMBL8320498 | 0.80 | RORC (0.43) | RORCLIPGLIPCCSNK1DDYRK1A | |
| SCHEMBL8320509 | 0.77 | HCRTR1 (0.31) | CA12CA1CA2 | |
| SCHEMBL6234746 | 0.75 | MMP2 (0.44) | RORCLIPGLIPCCSNK1DMMP3 | |
| SCHEMBL8312860 | 0.74 | RORC (0.37) | RORCNPC1RAB9ACYP2C9SMN1; SMN2 | |
| SCHEMBL6230548 | 0.73 | MMP13 (0.41) | RORCNPC1RAB9ATP53CYP2C9 | |
| SCHEMBL6230523 | 0.73 | MMP2 (0.46) | RORCSMN1; SMN2MMP3MMP9MMP8 | |
| SCHEMBL8320080 | 0.72 | SCN9A (0.41) | CASRNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL8312513 | 0.72 | MMP13 (0.45) | RORCMMP3MMP9MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |