Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.46 |
| ▸ | PDE1A | P54750 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316752 | 0.84 | TYMS (0.45) | DCTPP1KDM4EALDH1A1MAPTTYMS | |
| SCHEMBL2475307 | 0.81 | ALDH1A1 (0.51) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8315901 | 0.80 | ALDH1A1 (0.54) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8311879 | 0.79 | GABRA1 (0.44) | KDM4EALDH1A1MAPTALOX15TYMS | |
| SCHEMBL8312892 | 0.75 | TYMS (0.58) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL6085466 | 0.70 | CCR2 (0.67) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8316587 | 0.70 | ALDH1A1 (0.50) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL27204179 | 0.70 | KDM4E (0.58) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8924914 | 0.69 | KDM4E (1.00) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8318381 | 0.68 | KMT2A (0.42) | KDM4EALDH1A1MAPTTYMSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609328-B1 | PYRROLO-PYRIDAZINES WITH GASTRO-INTESTINAL PROTECTIVE ACTION | BYK GULDEN LOMBERG CHEM FAB (DE) | 1999-04-28 | — | — | EP | disclosed |
| US-5534515-A | Pyrrolopyridazines having gastrointestinal protective effects | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-07-09 | — | — | US | disclosed |
| WO-1993008190-A1 | PYRROLO-PYRIDAZINES WITH GASTRO-INTESTINAL PROTECTIVE ACTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-04-29 | — | — | WO | disclosed |