Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.56 |
| ▸ | PRKCA | P17252 | 7/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.46 |
| ▸ | PRKCG | P05129 | 3/20 | 0.46 |
| ▸ | PRKCB | P05771 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | PRKACA | P17612 | 3/20 | 0.46 |
| ▸ | PRKACG | P22612 | 3/20 | 0.46 |
| ▸ | PRKACB | P22694 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | PRKCH | P24723 | 3/20 | 0.46 |
| ▸ | PRKCI | P41743 | 3/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635747 | 0.73 | PRKCQ (0.61) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL18635720 | 0.73 | PRKCQ (0.61) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL14525823 | 0.72 | ROCK2 (0.70) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL20048218 | 0.71 | ROCK2 (0.64) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL8314778 | 0.70 | NQO1 (0.66) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL12856299 | 0.70 | PRKCQ (0.61) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL10965798 | 0.69 | NPSR1 (0.48) | MEN1MAPTKMT2A | |
| SCHEMBL10017809 | 0.69 | ROCK2 (0.64) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL8318323 | 0.68 | NQO1 (0.59) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL14708743 | 0.66 | PRKCA (0.52) | ROCK2PRKCAPRKCQPRKCDPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |