Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.64 |
| ▸ | PRKCA | P17252 | 8/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.50 |
| ▸ | PRKCG | P05129 | 4/20 | 0.50 |
| ▸ | PRKCB | P05771 | 4/20 | 0.50 |
| ▸ | PRKCH | P24723 | 4/20 | 0.50 |
| ▸ | PRKCI | P41743 | 4/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.50 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.50 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.50 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | PRKACG | P22612 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525823 | 0.76 | ROCK2 (0.70) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL8314778 | 0.73 | NQO1 (0.66) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL5438544 | 0.70 | PRKCA (0.71) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL14499964 | 0.70 | ROCK2 (0.57) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL8314407 | 0.69 | ROCK2 (0.56) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL15959912 | 0.68 | NQO1 (0.58) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL13169899 | 0.68 | ROCK2 (0.54) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| SCHEMBL8317372 | 0.68 | PRKCA (1.00) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| Staurosporinone SCHEMBL29374983 | 0.67 | MAP3K11 (1.00) | ROCK2PRKCAPRKCQPRKCDPRKD3 | |
| Staurosporinone SCHEMBL5440281 | 0.67 | MAP3K11 (1.00) | ROCK2PRKCAPRKCQPRKCDPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028309-A1 | Method for producing indole derivative | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |