Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.62 |
| ▸ | PRKCA | P17252 | 6/20 | 0.51 |
| ▸ | CDK4 | P11802 | 3/20 | 0.51 |
| ▸ | CCND1 | P24385 | 3/20 | 0.51 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.51 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | PRKCG | P05129 | 2/20 | 0.51 |
| ▸ | PRKCB | P05771 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | PRKACG | P22612 | 2/20 | 0.51 |
| ▸ | PRKACB | P22694 | 2/20 | 0.51 |
| ▸ | PRKCH | P24723 | 2/20 | 0.51 |
| ▸ | PRKCI | P41743 | 2/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499964 | 0.87 | ROCK2 (0.57) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL13169899 | 0.82 | ROCK2 (0.54) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL8313203 | 0.80 | NQO1 (1.00) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL14525823 | 0.77 | ROCK2 (0.70) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL10017809 | 0.73 | ROCK2 (0.64) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL8314407 | 0.70 | ROCK2 (0.56) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL8318191 | 0.69 | PRKCA (0.67) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL8317372 | 0.68 | PRKCA (1.00) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL5438544 | 0.68 | PRKCA (0.71) | NQO1ROCK2PRKCACDK4CCND1 | |
| SCHEMBL9623177 | 0.68 | NQO1 (0.71) | NQO1ROCK2PRKCACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |
| EP-0630242-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | claimed |
| WO-1993018766-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | claimed |
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5547976-A | VIRICIDES, HERPES VIRUS, CYTOMEGALOVIRUS; CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. (US) | 1996-08-20 | — | — | US | disclosed |