Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.59 |
| ▸ | PRKCA | P17252 | 5/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 4/20 | 0.48 |
| ▸ | CCND1 | P24385 | 4/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.48 |
| ▸ | PRKCG | P05129 | 3/20 | 0.48 |
| ▸ | PRKCB | P05771 | 3/20 | 0.48 |
| ▸ | PRKACA | P17612 | 3/20 | 0.48 |
| ▸ | PRKACG | P22612 | 3/20 | 0.48 |
| ▸ | PRKACB | P22694 | 3/20 | 0.48 |
| ▸ | PRKCH | P24723 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 3/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708743 | 0.75 | PRKCA (0.52) | NQO1PRKCAROCK2CDK4CCND1 | |
| SCHEMBL8313203 | 0.74 | NQO1 (1.00) | NQO1PRKCAROCK2CYP1B1CDK4 | |
| SCHEMBL8313138 | 0.72 | SIRT2 (0.59) | PRKCACYP1B1CDK4CCND1PRKD3 | |
| SCHEMBL5438544 | 0.71 | PRKCA (0.71) | NQO1PRKCAROCK2CDK4CCND1 | |
| SCHEMBL8317372 | 0.71 | PRKCA (1.00) | NQO1PRKCAROCK2CDK4CCND1 | |
| SCHEMBL30657539 | 0.71 | CYP1B1 (0.62) | CYP1B1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL8247166 | 0.71 | CYP1B1 (0.62) | CYP1B1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL15090840 | 0.70 | CYP1A2 (0.57) | JAK3KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL8312241 | 0.69 | NQO1 (0.66) | NQO1PRKCAROCK2CYP1B1CDK4 | |
| SCHEMBL8318191 | 0.69 | PRKCA (0.67) | NQO1PRKCAROCK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |