Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015224 | 0.74 | TNF (0.51) | HTR2CSLC6A2SLC6A4 | |
| SCHEMBL4037060 | 0.74 | LMNA (0.43) | ALDH1A1LMNA | |
| SCHEMBL8314716 | 0.74 | HTR7 (0.48) | PRCPHTR2AHTR1AHTR7HTR5A | |
| Hydrochloric Acid SCHEMBL10600743 | 0.72 | HTR7 (0.47) | PRCPHTR2AHTR1AHTR7HTR5A | |
| SCHEMBL8314577 | 0.71 | SIGMAR1 (0.40) | PRCPHTR2AHTR1AHTR7HTR6 | |
| SCHEMBL8313295 | 0.70 | CHRM1 (0.55) | HTR2AHTR7HTR2CPARP10PARP11 | |
| Hydrochloric Acid SCHEMBL10601953 | 0.69 | HTR7 (0.42) | HTR2AHTR1AHTR7HTR6HTR2C | |
| SCHEMBL12751291 | 0.69 | IKBKB (0.51) | HTR2AHTR7HTR2CHTR2B | |
| SCHEMBL28292786 | 0.69 | LMNA (0.50) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL8316812 | 0.68 | NISCH (0.40) | PRCPHTR2AHTR1AHTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |