Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313606 | 0.88 | TP53 (0.56) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8311933 | 0.83 | ALDH1A1 (0.49) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8313214 | 0.82 | TP53 (0.47) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8312845 | 0.82 | RECQL (0.54) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8317573 | 0.80 | KMT2A (0.52) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8317248 | 0.78 | PTGS2 (0.52) | TP53MAPTALDH1A1RAB9AHDAC3 | |
| SCHEMBL8312914 | 0.76 | TP53 (0.53) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8312438 | 0.76 | PTGS2 (0.45) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8314971 | 0.76 | MAOB (0.48) | TP53MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL8311715 | 0.76 | L3MBTL1 (0.53) | MAPTPDE4BALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |