Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 6/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8314991 | 0.80 | RARA (0.35) | CDC7DBF4TRPM8RARARARB | |
| Hydrochloric Acid SCHEMBL8312117 | 0.78 | RAB9A (0.42) | ALOX5MAPTRAB9ANPC1PKM | |
| SCHEMBL8315862 | 0.78 | ALOX5 (0.44) | ALOX5MAPTRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8315893 | 0.74 | MAPT (0.38) | ALOX5TRPM8MAPTRAB9ANPC1 | |
| SCHEMBL8022992 | 0.73 | MGAM (0.46) | RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8316299 | 0.73 | LOXL2 (0.39) | — | |
| SCHEMBL8312025 | 0.73 | L3MBTL1 (0.43) | CA2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8310827 | 0.72 | PIK3CD (0.40) | CDC7DBF4MAPTRAB9ANPC1 | |
| SCHEMBL8312319 | 0.72 | NPC1 (0.37) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL8314142 | 0.70 | NISCH (0.42) | MAPTRAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5118806-A | Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4956360-A | LIPOPEROXIDE INHIBITORS, ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0351856-A2 | Thiazolo[5,4-b]azepine compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |