Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | DRD4 | P21917 | 8/20 | 0.41 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636277 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BCA2LMNADRD2 | |
| SCHEMBL8322381 | 0.89 | LMNA (0.43) | ITGB3ITGA2BLMNADRD1PARP10 | |
| SCHEMBL7629751 | 0.80 | LMNA (0.43) | ITGB3ITGA2BCA2LMNADRD2 | |
| SCHEMBL7631192 | 0.79 | CA2 (0.57) | CA2LMNADRD2DRD4DRD3 | |
| SCHEMBL6855344 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BLMNADRD2DRD4 | |
| SCHEMBL7627971 | 0.77 | RAB9A (0.46) | ITGB3ITGA2BDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL6855339 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2BLMNADRD2DRD4 | |
| SCHEMBL8458648 | 0.75 | ITGB3 (0.40) | ITGB3ITGA2BCA2LMNADRD2 | |
| SCHEMBL10366696 | 0.75 | TDP1 (0.48) | ITGB3ITGA2BDRD2DRD4DRD3 | |
| SCHEMBL27280906 | 0.75 | TDP1 (0.48) | ITGB3ITGA2BDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | claimed |