Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317334 | 0.89 | ITGB3 (0.51) | LMNAPARP10ITGB3ITGA2BDRD1 | |
| SCHEMBL7636277 | 0.79 | ITGB3 (0.48) | LMNAITGB3ITGA2BTDP1DRD1 | |
| SCHEMBL7634224 | 0.78 | GPR35 (0.49) | RAB9A | |
| SCHEMBL7629779 | 0.76 | RAB9A (0.52) | LMNATDP1RAB9A | |
| SCHEMBL8454437 | 0.74 | TDP1 (0.47) | ITGB3ITGA2BTDP1 | |
| SCHEMBL7625167 | 0.74 | GPR35 (0.57) | — | |
| SCHEMBL5917881 | 0.73 | DRD2 (0.49) | LMNAITGB3ITGA2BL3MBTL1RAB9A | |
| SCHEMBL5917907 | 0.73 | DRD2 (0.49) | LMNAITGB3ITGA2BL3MBTL1RAB9A | |
| SCHEMBL28330075 | 0.72 | LMNA (0.44) | LMNAPTPN1CDC25BL3MBTL1OPRM1 | |
| SCHEMBL28330072 | 0.72 | LMNA (0.44) | LMNAPTPN1CDC25BL3MBTL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | claimed |