Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317963 | 0.87 | S1PR2 (0.44) | ALDH1A1CNR2LMNAMAPTS1PR2 | |
| SCHEMBL8324893 | 0.86 | KDM4E (0.41) | POLBS1PR2S1PR3GAAKDM4E | |
| SCHEMBL8321301 | 0.85 | HPGDS (0.43) | ALDH1A1POLBLMNAGAAACACB | |
| SCHEMBL8318943 | 0.77 | HSD17B2 (0.32) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL8317483 | 0.75 | ALDH1A1 (0.52) | ALDH1A1POLBCNR2LMNAMAPT | |
| SCHEMBL8317419 | 0.72 | HPGD (0.54) | ALDH1A1POLBCNR2LMNAMAPT | |
| SCHEMBL8313475 | 0.71 | ALDH1A1 (0.48) | ALDH1A1POLBCNR2LMNAMAPT | |
| SCHEMBL2934366 | 0.70 | SRC (0.46) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL8320373 | 0.70 | HDAC1 (0.57) | ALDH1A1POLBCNR2LMNAMAPT | |
| SCHEMBL8317996 | 0.68 | TP53 (0.46) | ALDH1A1LMNAMAPTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |