Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324891 | 0.82 | OPRM1 (0.36) | MAPK1 | |
| SCHEMBL8322242 | 0.81 | CHRNB2 (0.37) | MEN1KMT2A | |
| SCHEMBL8318902 | 0.77 | ALDH1A1 (0.47) | HSD17B2LMNATP53GAAMAPT | |
| SCHEMBL8317994 | 0.76 | CYP3A4 (0.43) | HSD17B2MEN1MAPTMAPK1HTT | |
| SCHEMBL8317963 | 0.74 | S1PR2 (0.44) | MEN1LMNATP53GAAMAPT | |
| SCHEMBL27796397 | 0.73 | ALDH1A1 (0.38) | KIF11MEN1LMNATP53MAPT | |
| SCHEMBL9680972 | 0.72 | ALDH1A1 (0.49) | MEN1USP2TP53MAPTALOX15 | |
| SCHEMBL8388890 | 0.72 | ALDH1A1 (0.48) | MEN1TP53GAAMAPTALOX15 | |
| SCHEMBL10349155 | 0.72 | ALDH1A1 (0.58) | MEN1USP2TP53GAAMAPT | |
| SCHEMBL8317419 | 0.70 | HPGD (0.54) | MEN1LMNATP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |