Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319747 | 0.97 | POLB (0.46) | POLBGAAKDM4EHPGDNPSR1 | |
| SCHEMBL8320047 | 0.86 | KDM4E (0.48) | GAAKDM4EHPGDNPSR1ALDH1A1 | |
| SCHEMBL8317255 | 0.84 | GAA (0.45) | POLBGAAKDM4EHPGDNPSR1 | |
| SCHEMBL8086890 | 0.83 | NPSR1 (0.65) | POLBGAAKDM4EHPGDNPSR1 | |
| SCHEMBL8318729 | 0.81 | GAA (0.44) | POLBGAAKDM4EHPGDNPSR1 | |
| SCHEMBL8323687 | 0.79 | HPGD (0.55) | POLBGAAKDM4EHPGDNPSR1 | |
| SCHEMBL8323187 | 0.78 | MEN1 (0.54) | POLBNPSR1MEN1KMT2ACYP3A4 | |
| SCHEMBL8192331 | 0.75 | MEN1 (0.53) | POLBNPSR1MEN1KMT2ACYP3A4 | |
| SCHEMBL8318029 | 0.72 | ALDH1A1 (0.46) | GAAKDM4EHPGDNPSR1MEN1 | |
| SCHEMBL8318492 | 0.69 | LMNA (0.44) | GAAKDM4EHPGDNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717043-B1 | Use of 1,2-bridged 1,4-dihydropyridines as selective potassium channel modulators | BAYER AG (DE) | 1999-11-10 | — | — | EP | claimed |