Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319794 | 0.86 | POLB (0.47) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8318029 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8319747 | 0.83 | POLB (0.46) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8318492 | 0.83 | LMNA (0.44) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8323687 | 0.75 | HPGD (0.55) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL12135876 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8086890 | 0.72 | NPSR1 (0.65) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8317255 | 0.71 | GAA (0.45) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8325253 | 0.71 | KMT2A (0.39) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL28054886 | 0.70 | ALDH1A1 (0.54) | ALDH1A1GAALMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717043-B1 | Use of 1,2-bridged 1,4-dihydropyridines as selective potassium channel modulators | BAYER AG (DE) | 1999-11-10 | — | — | EP | claimed |