Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898422 | 0.83 | G6PD (0.64) | MEN1KMT2ATDP1G6PDIDE | |
| Sulfuric Acid SCHEMBL7560875 | 0.81 | KMT2A (0.70) | MEN1KMT2ATDP1PKMALDH1A1 | |
| SCHEMBL10300269 | 0.80 | PTGS2 (0.62) | KIF11PTGS2ENPP2 | |
| SCHEMBL7677302 | 0.80 | PTGS2 (0.62) | KIF11PTGS2ENPP2 | |
| SCHEMBL5309806 | 0.79 | IKBKB (0.63) | KMT2ADHFRKDM4ELRRK2MAP4K4 | |
| SCHEMBL5302192 | 0.79 | LRRK2 (0.49) | G6PDIDEDHFRKIF11PTGS2 | |
| SCHEMBL5673147 | 0.79 | TDP1 (0.71) | MEN1KMT2ATDP1G6PDIDE | |
| SCHEMBL5316043 | 0.79 | CA12 (0.64) | TDP1DHFRPTGS2ALDH1A1GAA | |
| SCHEMBL12772920 | 0.78 | TDP1 (0.93) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL12740176 | 0.77 | CA2 (0.71) | DHFRKIF11PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |