Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325686 | 0.86 | LMNA (0.58) | CYP4A11CYP4F2LMNAMAPTRAB9A | |
| SCHEMBL8324027 | 0.82 | MAPT (0.59) | CYP4A11CYP4F2LMNAMAPTRAB9A | |
| SCHEMBL8565733 | 0.78 | CYP4A11 (0.54) | CYP4A11CYP4F2LMNAMAPTRAB9A | |
| SCHEMBL8319293 | 0.78 | CYP4A11 (0.60) | CYP4A11CYP4F2LOXL2ALDH1A1TP53 | |
| SCHEMBL8318954 | 0.77 | LMNA (0.63) | CYP4A11CYP4F2LMNAMAPTRAB9A | |
| SCHEMBL8676594 | 0.76 | TDP1 (0.54) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL10397856 | 0.75 | MAPT (0.66) | CYP4A11CYP4F2LMNAMAPT | |
| SCHEMBL9176869 | 0.75 | MAPT (0.57) | LMNAMAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8977828 | 0.75 | MAPT (0.57) | LMNAMAPTRAB9AL3MBTL1LOXL2 | |
| SCHEMBL14967232 | 0.74 | L3MBTL1 (0.53) | CYP4A11CYP4F2LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |