Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093738 | 0.83 | MIF (0.43) | LMNATSHRTAAR1 | |
| SCHEMBL8324360 | 0.82 | HDAC4 (0.40) | MAPTALOX12TP53TDP1TAAR1 | |
| SCHEMBL8327671 | 0.82 | LMNA (0.42) | ACHEMAPTNPSR1OPRM1OPRD1 | |
| SCHEMBL8330722 | 0.79 | IDO1 (0.46) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8319057 | 0.79 | ACP3 (0.45) | ACP3MAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL8323859 | 0.79 | MAOA (0.41) | MAPTLMNATSHRCYP19A1TDP1 | |
| SCHEMBL4371427 | 0.79 | ACHE (0.52) | ACP3EPHX1ACHEMAPTNPSR1 | |
| SCHEMBL6548082 | 0.78 | ACP3 (0.44) | ACP3EPHX1ACHEMAPTLMNA | |
| SCHEMBL3931572 | 0.77 | ACHE (0.50) | ACP3EPHX1ACHEMAPTNPSR1 | |
| Isopropylbenzene SCHEMBL22653317 | 0.75 | ACP3 (0.52) | ACP3EPHX1ACHEMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |