Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323792 | 0.82 | SLC6A2 (0.50) | TRPA1SLC6A2TAAR1ALDH1A1LMNA | |
| SCHEMBL8321757 | 0.81 | SLC6A2 (0.48) | TRPA1SLC6A2TAAR1MAPTALDH1A1 | |
| SCHEMBL2671508 | 0.78 | LTA4H (0.60) | LTA4HSLC6A2TAAR1ALDH1A1KMT2A | |
| SCHEMBL8323288 | 0.78 | TAAR1 (0.46) | SLC6A2TAAR1MAPTALDH1A1LMNA | |
| SCHEMBL8323216 | 0.78 | SLC6A2 (0.46) | SLC6A2TAAR1MAPTALDH1A1KDM4E | |
| SCHEMBL5305755 | 0.76 | LTA4H (0.52) | LTA4HSLC6A2TAAR1ALDH1A1MMP1 | |
| SCHEMBL17964410 | 0.73 | LTA4H (0.53) | LTA4HSLC6A2TAAR1ALDH1A1LMNA | |
| SCHEMBL8324902 | 0.73 | MAOB (0.49) | TRPA1SLC6A2TAAR1MAPTLMNA | |
| SCHEMBL8976499 | 0.72 | LTA4H (0.52) | LTA4HSLC6A2TAAR1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11263398 | 0.72 | LTA4H (0.52) | LTA4HSLC6A2TAAR1ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |