SCHEMBL8325762

SCHEMBL8325762

Cc1ccc(N(c2ccccc2)C2(N(c3ccccc3)c3ccc(C)cc3C)C=CC(c3ccccc3)C=C2)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.33
DRD4 P21917 5/20 0.33
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1255774 0.83 CYP2C19 (0.35) LMNA
SCHEMBL710236 0.82 ALDH1A1 (0.33) HTT
SCHEMBL2790033 0.81 CYP2C19 (0.36) LMNA
SCHEMBL9190411 0.80 TSPO (0.31)
SCHEMBL1144651 0.77 RAB9A (0.30) HTT
SCHEMBL15514366 0.77 RAB9A (0.30) HTT
SCHEMBL9192421 0.77 ACHE (0.33) HTT
SCHEMBL6761166 0.76 RAB9A (0.31) LMNAHTT
SCHEMBL6257255 0.74
SCHEMBL6711335 0.73 PKM (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699654-B1 Hole-transporting material and use thereof TOYO INK MFG CO (JP) 1999-03-31 EP disclosed
US-5681664-A CONTAINING A POLYAMINE TOYO INK MANUFACTURING CO., LTD. (JP) 1997-10-28 US disclosed
EP-0699654-A1 Hole-transporting material TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-06 EP disclosed