Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523243 | 0.85 | GPR119 (0.47) | PTPN2PTPN1KMT2AGAAMAPT | |
| SCHEMBL8605663 | 0.82 | GPR119 (0.39) | THRBRAB9ANPC1MCL1PTPN2 | |
| SCHEMBL8325991 | 0.76 | P2RY14 (0.48) | RAB9ANPC1MCL1KMT2AMAPT | |
| SCHEMBL8463058 | 0.76 | L3MBTL3 (0.57) | NPC1KMT2AGAAHPGDHSD17B10 | |
| SCHEMBL8666469 | 0.75 | MAPT (0.44) | PTPN2PTPN1KMT2AGAAMAPT | |
| SCHEMBL8318616 | 0.74 | USP2 (0.52) | RAB9AKMT2AGPR183GAAMAPT | |
| SCHEMBL8321062 | 0.73 | KIT (0.48) | MCL1KMT2AHSD17B10MAPT | |
| SCHEMBL9058915 | 0.72 | MAPT (0.46) | THRBKMT2AMAPT | |
| SCHEMBL16178434 | 0.72 | RAB9A (0.47) | THRBRAB9ANPC1KMT2A | |
| SCHEMBL8666467 | 0.69 | SMN1; SMN2 (0.45) | PTPN2PTPN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |