Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463058 | 0.85 | L3MBTL3 (0.57) | GAAMEN1KMT2ATPSAB1TPSD1 | |
| SCHEMBL8325925 | 0.74 | THRB (0.44) | GAAGPR183KMT2ARAB9AMAPT | |
| SCHEMBL15400302 | 0.72 | SIGMAR1 (0.54) | GAAMEN1KMT2ATPSAB1TPSD1 | |
| SCHEMBL27382331 | 0.72 | SIGMAR1 (0.59) | GAAMEN1KMT2ATPSAB1TPSD1 | |
| SCHEMBL7402423 | 0.72 | USP2 (0.54) | USP2GAAGPR183MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7358202 | 0.72 | MAPK1 (0.51) | USP2GAAMEN1KMT2ATPSAB1 | |
| SCHEMBL9832704 | 0.70 | ALOX15 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3673014 | 0.70 | SMN1; SMN2 (0.58) | MEN1KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL9058915 | 0.70 | MAPT (0.46) | MEN1KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL13801429 | 0.70 | ITGB3 (0.69) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |