Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327662 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4ESPHK2SPHK1SLC6A4 | |
| SCHEMBL8325593 | 0.77 | SPHK2 (0.41) | ALDH1A1SPHK2SPHK1MAPK1CRHBP | |
| SCHEMBL8330331 | 0.74 | SPHK2 (0.45) | ALDH1A1KDM4ESPHK2SPHK1MAPK1 | |
| SCHEMBL8328585 | 0.69 | ALDH1A1 (0.34) | ALDH1A1KDM4ESPHK2SPHK1SLC6A4 | |
| SCHEMBL10462905 | 0.69 | SPHK2 (0.50) | ALDH1A1KDM4ESPHK2SPHK1MAPK1 | |
| SCHEMBL8621242 | 0.68 | SPHK2 (0.38) | ALDH1A1SPHK2SPHK1MAPK1SMN1; SMN2 | |
| SCHEMBL8325591 | 0.68 | OPRM1 (0.40) | ALDH1A1SPHK2SPHK1 | |
| SCHEMBL8621224 | 0.68 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ACTSS | |
| SCHEMBL8327242 | 0.68 | SPHK2 (0.49) | ALDH1A1KDM4ESPHK2SPHK1MAPK1 | |
| SCHEMBL16225834 | 0.67 | MEN1 (0.55) | SPHK2SPHK1SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |