Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969347 | 0.85 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13201300 | 0.85 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL3162410 | 0.83 | LMNA (0.50) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13201342 | 0.83 | MMP2 (0.52) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13217834 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL8319712 | 0.76 | ATM (0.51) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL2961185 | 0.76 | ATM (0.51) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL3153829 | 0.73 | KDM4E (0.47) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL8319435 | 0.73 | MMP2 (0.48) | ALDH1A1LMNAHTTCA12CA1 | |
| SCHEMBL13218222 | 0.73 | GAA (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585728-B1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2004060874-A1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | WO | disclosed |