Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CDC7 | O00311 | 4/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328608 | 0.92 | KMT2A (0.44) | SMN1; SMN2NPSR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL8332614 | 0.82 | CCNC (0.46) | SMN1; SMN2NPSR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL8331317 | 0.81 | PPARA (0.55) | PPARGPPARA | |
| SCHEMBL5711752 | 0.78 | TDP1 (0.54) | SMN1; SMN2NPSR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7694497 | 0.75 | ALDH1A1 (0.57) | SMN1; SMN2KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8949976 | 0.75 | MAPT (0.54) | SMN1; SMN2KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27496395 | 0.73 | MMP8 (0.51) | NPSR1KMT2AALDH1A1CDC7DBF4 | |
| SCHEMBL855858 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2NPSR1KMT2ALMNAL3MBTL1 | |
| SCHEMBL8332612 | 0.73 | CCNC (0.49) | NPSR1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7329538 | 0.73 | TAS1R3 (0.51) | SMN1; SMN2LDHANPSR1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |