Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332307 | 0.89 | ACHE (0.43) | CCR5 | |
| SCHEMBL8333855 | 0.84 | CYSLTR2 (0.49) | KDM4E | |
| SCHEMBL8329453 | 0.84 | CYSLTR2 (0.49) | KDM4E | |
| SCHEMBL8334139 | 0.84 | ALDH1A1 (0.43) | KDM4E | |
| SCHEMBL8333192 | 0.83 | KCNQ2 (0.46) | KCNQ2CCR5AOC3 | |
| SCHEMBL8332918 | 0.82 | ALOX5 (0.44) | CCR5KDM4E | |
| SCHEMBL8721505 | 0.82 | KDM4E (0.46) | CCR5L3MBTL1KDM4E | |
| SCHEMBL8331069 | 0.82 | CCR5 (0.39) | CCR5POLB | |
| SCHEMBL8333977 | 0.81 | ALDH1A1 (0.40) | KDM4ETDP1 | |
| SCHEMBL8331870 | 0.81 | KDM4E (0.38) | KCNQ2CCR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |