Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | USP9X | Q93008 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329361 | 0.86 | CCR5 (0.49) | CCR5SMN1; SMN2MEN1KMT2APTGS2 | |
| SCHEMBL8333192 | 0.85 | KCNQ2 (0.46) | CCR5MEN1KMT2ADPP4DPP9 | |
| SCHEMBL8332215 | 0.82 | POLB (0.49) | SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8328657 | 0.82 | KCNQ2 (0.47) | CCR5POLB | |
| SCHEMBL8332307 | 0.81 | ACHE (0.43) | CCR5MEN1KMT2ADPP4DPP9 | |
| SCHEMBL8332918 | 0.80 | ALOX5 (0.44) | CCR5SMN1; SMN2 | |
| SCHEMBL8331939 | 0.79 | KCNQ2 (0.41) | CCR5SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8333540 | 0.78 | MTNR1A (0.46) | CCR5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8329274 | 0.77 | MTNR1A (0.45) | CCR5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8330948 | 0.77 | MTNR1A (0.45) | CCR5SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |