Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326114 | 0.81 | MEN1 (0.48) | CHRM2 | |
| SCHEMBL8329414 | 0.79 | SIGMAR1 (0.53) | ACHE | |
| SCHEMBL8329774 | 0.78 | MAPK1 (0.48) | MAPK1FAAH | |
| SCHEMBL8328601 | 0.77 | BCHE (0.41) | FAAHDRD4ACHE | |
| SCHEMBL24323784 | 0.76 | CARM1 (0.59) | MAPK1 | |
| SCHEMBL8326334 | 0.76 | KMT2A (0.56) | — | |
| SCHEMBL7488935 | 0.75 | DRD3 (0.51) | DRD4 | |
| SCHEMBL23751084 | 0.74 | MAPK1 (0.55) | MAPK1FAAH | |
| SCHEMBL8328840 | 0.72 | CARM1 (0.42) | MAPK1 | |
| SCHEMBL8325591 | 0.72 | OPRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |