Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329817 | 0.83 | VNN1 (0.43) | KDM6BKDM4CVNN1NAMPTHDAC8 | |
| SCHEMBL28679564 | 0.74 | TRPV1 (0.54) | KDM6BKDM4CCSNK2A2CSNK2A1NAMPT | |
| SCHEMBL30874169 | 0.73 | ALDH1A1 (0.49) | HDAC8HDAC6HDAC1L3MBTL1RAB9A | |
| SCHEMBL10690524 | 0.73 | HCAR3 (0.57) | KDM6BKDM4CHDAC8HDAC6HDAC1 | |
| SCHEMBL21409362 | 0.73 | ALDH1A1 (0.49) | HDAC8HDAC6HDAC1L3MBTL1RAB9A | |
| SCHEMBL6845399 | 0.72 | MRGPRX4 (0.55) | KDM4CVNN1 | |
| SCHEMBL8996251 | 0.72 | TBXAS1 (0.58) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5307781 | 0.71 | LTA4H (0.69) | L3MBTL1APAF1PABPC1CASP6CASP8 | |
| SCHEMBL1116010 | 0.71 | KDM6B (0.59) | KDM6BKDM4CHDAC8HDAC6HDAC1 | |
| SCHEMBL5353235 | 0.70 | TBXAS1 (0.62) | L3MBTL1PTAFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |