Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329643 | 0.69 | CES1 (0.42) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL8327028 | 0.67 | RAB9A (0.36) | — | |
| SCHEMBL29689350 | 0.61 | CES1 (0.42) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL2973373 | 0.61 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL505409 | 0.60 | S100A4 (0.55) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL8329359 | 0.59 | CES1 (0.43) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL8330728 | 0.59 | CES1 (0.43) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL13058018 | 0.58 | ALDH1A1 (0.50) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL3754645 | 0.58 | CES1 (0.59) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL31355582 | 0.58 | CES1 (0.42) | CES1DAONSD2BCHELIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529636-B1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1999-06-23 | — | — | EP | disclosed |
| US-5436250-A | Isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1995-07-25 | — | — | US | disclosed |
| US-5242918-A | Isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-07 | — | — | US | disclosed |
| WO-1993005043-A1 | NOVEL ISATINOXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1993-03-18 | — | — | WO | disclosed |
| EP-0529636-A1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-03-03 | — | — | EP | disclosed |