Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328095 | 0.85 | MEN1 (0.42) | SLC6A1L3MBTL1SLC6A11ALDH1A1GAA | |
| SCHEMBL8331026 | 0.83 | TK1 (0.38) | SLC6A1SLC6A11PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL14197473 | 0.81 | ADRB2 (0.45) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL25034637 | 0.81 | TDP1 (0.41) | ALDH1A1MEN1KMT2AMAPTPNLIP | |
| SCHEMBL29894147 | 0.78 | PLA2G2A (0.35) | SLC6A1SLC6A11PLA2G2APLA2G10PLA2G1B | |
| SCHEMBL27081229 | 0.76 | MAPT (0.42) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL27081233 | 0.76 | MAPT (0.42) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL7721078 | 0.76 | TBXAS1 (0.44) | SLC6A1SLC6A11KMT2AMAPTNPC1 | |
| SCHEMBL21647836 | 0.76 | TBXAS1 (0.41) | L3MBTL1ALDH1A1GAACYP19A1MAPK1 | |
| SCHEMBL21647837 | 0.76 | TBXAS1 (0.41) | L3MBTL1ALDH1A1GAACYP19A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523978-B1 | Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides | JOLLA PHARMA (US) | 1999-05-12 | — | — | EP | disclosed |
| US-5874552-A | Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| US-5786512-A | Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides | LAJOLLA PHARMACEUTICAL COMPANY (US) | 1998-07-28 | — | — | US | disclosed |
| US-5726329-A | Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5391785-A | Intermediates for providing functional groups on the 5' end of oligonucleotides | LA JOLLA PHARMACEUTIAL COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0523978-A1 | Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides | LA JOLLA PHARMACEUTICAL (US) | 1993-01-20 | — | — | EP | disclosed |