Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410599 | 0.91 | LMNA (0.48) | NOD2LMNA | |
| SCHEMBL8329943 | 0.88 | NOD2 (0.48) | EPHX2LTA4HMAPK10NOD2RORC | |
| SCHEMBL9231797 | 0.87 | MAPT (0.45) | NOD2RORCMAPTABL1BCR | |
| SCHEMBL15684817 | 0.84 | EPHX2 (0.46) | EPHX2LTA4HMAPK8MAPK10KDR | |
| SCHEMBL8413441 | 0.84 | NOD2 (0.44) | MAPK8MAPK10NOD2LMNARORC | |
| SCHEMBL3549808 | 0.81 | PLAAT3 (0.47) | LMNA | |
| SCHEMBL8412094 | 0.80 | NOD2 (0.44) | NOD2LMNAL3MBTL1RIOK2 | |
| SCHEMBL3540389 | 0.80 | PLAAT3 (0.52) | LMNA | |
| SCHEMBL8331056 | 0.78 | NLRP3 (0.45) | NOD2CNR2MAPTRETRIOK2 | |
| SCHEMBL27550688 | 0.78 | NOD2 (0.49) | EPHX2LTA4HMAPK8MAPK10NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5597836-A | NEMATOCIDES, INSECTICIDES, MITICIDES AND PLANT PATHOGENS | DOWELANCO (US) | 1997-01-28 | — | — | US | disclosed |