Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IL18 | Q14116 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329943 | 0.88 | NOD2 (0.48) | NOD2RORCKMT2ARAB9AMEN1 | |
| SCHEMBL8667377 | 0.84 | CACNA1H (0.41) | CACNA1HRORCS1PR1S1PR3KMT2A | |
| SCHEMBL8330868 | 0.84 | EPHX2 (0.46) | NOD2RORCLMNAMAPTMAPK8 | |
| SCHEMBL8412094 | 0.80 | NOD2 (0.44) | NOD2KMT2ARAB9AMEN1LMNA | |
| SCHEMBL8331056 | 0.78 | NLRP3 (0.45) | NOD2CACNA1HKMT2ARAB9AMEN1 | |
| SCHEMBL27550688 | 0.78 | NOD2 (0.49) | NOD2KMT2ARAB9AMEN1MAPK8 | |
| SCHEMBL8987819 | 0.77 | MAPK10 (0.45) | CACNA1HRORCKMT2ARAB9AMEN1 | |
| SCHEMBL8410599 | 0.77 | LMNA (0.48) | NOD2RAB9ALMNA | |
| SCHEMBL9231797 | 0.77 | MAPT (0.45) | NOD2RORCMAPTROCK2L3MBTL1 | |
| SCHEMBL8412024 | 0.76 | L3MBTL1 (0.47) | NOD2KMT2ARAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822930-B1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5763463-A | Pyridine compounds which are useful as pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0822930-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033975-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |