Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421589 | 0.79 | CYP4F2 (0.47) | CYP4F2CYP4A11SLC5A1SLC5A2SIGMAR1 | |
| SCHEMBL1691998 | 0.72 | SMYD3 (0.49) | SMN1; SMN2SMYD3NPC1RAB9AKMT2A | |
| SCHEMBL8469011 | 0.72 | SLC5A1 (0.41) | MGLLSLC5A1SLC5A2SMN1; SMN2SIGMAR1 | |
| SCHEMBL8469013 | 0.72 | SLC5A1 (0.41) | MGLLSLC5A1SLC5A2SMN1; SMN2SIGMAR1 | |
| SCHEMBL8329361 | 0.69 | CCR5 (0.49) | SMN1; SMN2SMYD3KMT2A | |
| SCHEMBL8331069 | 0.68 | CCR5 (0.39) | SMN1; SMN2SMYD3KMT2A | |
| SCHEMBL13534476 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2SMYD3NPC1RAB9AKMT2A | |
| SCHEMBL18617804 | 0.66 | SLC5A1 (0.37) | SLC5A1SLC5A2 | |
| SCHEMBL8098235 | 0.66 | MTNR1B (0.54) | SLC5A1SLC5A2 | |
| SCHEMBL8098232 | 0.66 | MTNR1B (0.54) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |