SCHEMBL8333376

SCHEMBL8333376

C[CH]S(=O)(=O)c1ccc(C#N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 5/20 0.50
▸ CA2 P00918 5/20 0.50
▸ CA9 Q16790 3/20 0.50
▸ CA12 O43570 2/20 0.50
▸ PTGS2 P35354 1/20 0.45
▸ CYP19A1 P11511 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ MAPT P10636 3/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ S100A4 P26447 1/20 0.43
▸ MTOR P42345 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ CYP2A6 P11509 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11330861 0.79 MAPT (0.53) CA1CA2CA9CA12PTGS2
SCHEMBL1332778 0.78 CA2 (0.57) CA1CA2CA9CA12PTGS2
SCHEMBL803901 0.76 PTGS2 (0.68) CA1CA2CA9CA12PTGS2
SCHEMBL8514633 0.75 CA2 (0.59) CA1CA2CA9CA12PTGS2
SCHEMBL343050 0.73 TLR9 (0.70) CA1CA2CA9CA12ALDH1A1
SCHEMBL1894003 0.73 CA2 (0.57) CA1CA2CA9CA12PTGS2
SCHEMBL9628592 0.72 CA2 (0.52) CA1CA2CA9CA12PTGS2
SCHEMBL506270 0.72 MAPT (0.55) CA1CA2CA9CA12PTGS2
SCHEMBL9752512 0.71 TSHR (0.54) CA1CA2CA9CA12ALDH1A1
SCHEMBL758697 0.71 CA2 (0.50) CA1CA2CA9CA12CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530957-B1 A lithographic printing plate precursor of direct image type FUJI PHOTO FILM CO LTD (JP) 1999-12-22 — — EP disclosed
US-5368931-A Support with image receiver layer matrix resin and particles, the polymer with silane and fluorine groups FUJI PHOTO FILM CO., LTD. (JP) 1994-11-29 — — US disclosed
EP-0326169-B1 Electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 1994-04-20 — — EP disclosed
EP-0284748-B1 Electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 1993-12-22 — — EP disclosed
EP-0341825-B1 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 1993-11-18 — — EP disclosed
EP-0530957-A1 A lithographic printing plate precursor of direct image type FUJI PHOTO FILM CO., LTD. (JP) 1993-03-10 — — EP disclosed
US-5017448-A Reduced background stain, durability, resin which decomposes to carboxyl groups FUJI PHOTO FILM CO., LTD. (JP) 1991-05-21 — — US disclosed
US-4971870-A OFFSET PRINTING, ELECTROCONDUCTORS, PHOTOCONDUCTORS, BINDER RESINS, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 — — US disclosed
US-4960661-A BINDER CONTAINING A CARBOXY-FORMING ACRYLIC RESIN, A HEAT OR LIGHT CURABLE RESIN AND A CROSSLINKER; NO BACKGROUND STAINS; PRINTING DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 — — US disclosed
EP-0341825-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 — — EP disclosed
US-4880716-A CARBOXY UNSATURATED RESIN; HYDROPHILIC FUJI PHOTO FILM CO., LTD. (JP) 1989-11-14 — — US disclosed
EP-0326169-A2 Electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1989-08-02 — — EP disclosed
US-4792511-A BASED ON A CARBOXYLIC ACID-FORMING MONOMER; OIL REPELLANTS; ANTISOILANTS; DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 — — US disclosed
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