Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341309 | 0.90 | ALDH1A1 (0.38) | CNR2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8334261 | 0.89 | CNR2 (0.39) | CNR2LMNAKMT2AMEN1HPGD | |
| SCHEMBL8339579 | 0.74 | LMNA (0.36) | CNR2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8341129 | 0.74 | CNR2 (0.35) | CNR2LMNAALDH1A1P2RX7 | |
| SCHEMBL8334265 | 0.70 | CNR2 (0.35) | CNR2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8338584 | 0.59 | HPGD (0.40) | CNR2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8339583 | 0.59 | — | — | |
| SCHEMBL8337202 | 0.58 | HPGD (0.39) | CNR2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8864625 | 0.57 | SLC6A2 (0.34) | KMT2AMEN1 | |
| SCHEMBL8864563 | 0.57 | KMT2A (0.37) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |