Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399203 | 0.86 | SIGMAR1 (0.49) | SIGMAR1MEN1KMT2ATP53LMNA | |
| SCHEMBL10404786 | 0.82 | LMNA (0.40) | SIGMAR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL5557095 | 0.80 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL29278837 | 0.79 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL8401055 | 0.74 | LMNA (0.36) | SIGMAR1ALDH1A1TAAR1LMNA | |
| SCHEMBL29285010 | 0.72 | GABRA1 (0.39) | SIGMAR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL8843004 | 0.71 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2ATP53LMNA | |
| SCHEMBL8332943 | 0.71 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2ATP53LMNA | |
| SCHEMBL6719598 | 0.70 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ATP53LMNA | |
| SCHEMBL4606083 | 0.70 | PARP1 (0.52) | SIGMAR1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | claimed |