Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404786 | 0.90 | LMNA (0.40) | LMNATAAR1IDO1GABRA1GABRB2 | |
| SCHEMBL9317579 | 0.79 | SIGMAR1 (0.38) | LMNASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29285010 | 0.76 | GABRA1 (0.39) | LMNATAAR1IDO1GABRA1GABRB2 | |
| SCHEMBL8332943 | 0.76 | SIGMAR1 (0.52) | LMNASIGMAR1MAPTCYP2D6 | |
| SCHEMBL8334067 | 0.75 | SIGMAR1 (0.37) | LMNAGABRA1GABRB2SIGMAR1GRIN2D | |
| SCHEMBL27984498 | 0.74 | PNMT (0.39) | LMNATAAR1IDO1GRIN2DGRIN3B | |
| SCHEMBL1955058 | 0.74 | LMNA (0.44) | LMNAGABRA1GABRB2NPSR1SIGMAR1 | |
| SCHEMBL8399203 | 0.74 | SIGMAR1 (0.49) | LMNASIGMAR1MAPTCYP2D6 | |
| SCHEMBL8337461 | 0.74 | RECQL (0.39) | LMNATAAR1SIGMAR1ALDH1A1 | |
| SCHEMBL9729315 | 0.72 | LMNA (0.38) | LMNAGABRA1GABRB2NPSR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | claimed |