Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555377 | 1.00 | NPC1 (0.78) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL29757180 | 0.88 | NPC1 (1.00) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL30743 | 0.88 | NPC1 (1.00) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL28053968 | 0.86 | RAB9A (0.72) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL12386953 | 0.85 | ALDH1A1 (0.72) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL443618 | 0.85 | NPC1 (0.84) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL30592751 | 0.85 | NPC1 (0.84) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL12075055 | 0.85 | NPC1 (0.84) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL10268204 | 0.85 | NPC1 (0.60) | NPC1POLBRAB9AALDH1A1DYRK1A | |
| SCHEMBL130884 | 0.84 | ALDH1A1 (1.00) | NPC1POLBRAB9AALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11759462-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | ALTAVANT SCIENCES GMBH | 2023-09-19 | — | — | US | disclosed |
| US-20210193935-A1 | P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES | SONY CORPORATION (JP) | 2021-06-24 | — | — | US | disclosed |
| WO-2021120838-A1 | ORGANIC COMPOUND, ELECTRONIC DEVICE, AND ELECTRONIC APPARATUS | 陕西莱特光电材料股份有限公司 | 2021-06-24 | — | — | WO | disclosed |
| WO-2021082714-A1 | NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE | 陕西莱特光电材料股份有限公司 | 2021-05-06 | — | — | WO | disclosed |
| EP-3041842-B1 | SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS | KAROS PHARMACEUTICALS INC (US) | 2019-10-23 | — | — | EP | disclosed |
| US-20180092918-A1 | SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS | ALTAVANT SCIENCES GMBH (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180092918-A1 | SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS | ALTAVANT SCIENCES GMBH (CH) | 2018-04-05 | — | — | US | disclosed |
| CN-107459535-A | Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof | 南京工业大学 | 2017-12-12 | — | — | CN | disclosed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |
| US-20110190494-A1 | 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT | TOSOH CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |
| US-7662845-B2 | 2,5-Dioxoimidazolidin-4-yl acetamides and analogues as inhibitors of metalloproteinase MMP12 | ASTRAZENECA AB (SE) | 2010-02-16 | — | — | US | disclosed |
| US-7662845-B2 | 2,5-Dioxoimidazolidin-4-yl acetamides and analogues as inhibitors of metalloproteinase MMP12 | ASTRAZENECA AB (SE) | 2010-02-16 | — | — | US | disclosed |
| US-20100021940-A1 | Method for Determining the Activity of a Protease in a Sample | ASTRAZENECA AB (SE) | 2010-01-28 | — | — | US | disclosed |
| US-20090066231-A1 | Electroluminescent device | UDC IRELAND LIMITED (IE) | 2009-03-12 | — | — | US | disclosed |
| US-7354940-B2 | 2,5-dioxoimidazolidin-4-yl acetamines and analogues as inhibitors of metalloproteinase mmp12 | ASTRAZENECA AB (SE) | 2008-04-08 | — | — | US | disclosed |
| US-7354940-B2 | 2,5-dioxoimidazolidin-4-yl acetamines and analogues as inhibitors of metalloproteinase mmp12 | ASTRAZENECA AB (SE) | 2008-04-08 | — | — | US | disclosed |
| WO-2004024060-A2 | METALLOPROTEINASE INHIBITORS AND INTERMEDIATES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004020415-A1 | 2,5-DIOXOIMIDAZOLIDIN-4-YL ACETAMIDES AND ANALOGUES AS INHIBITORS OF METALLOPROTEINASE MMP12. | ASTRAZENECA AB (SE) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092918-A1 | SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS | TPH1, TPH2, HTR1A | NPC1 2072/4885POLB 4133/4885RAB9A 2533/4885 |
| US-20100021940-A1 | Method for Determining the Activity of a Protease in a Sample | CTRL, PRSS1, PREP | NPC1 1131/4885POLB 3481/4885RAB9A 2355/4885 |
| US-11759462-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | TPH1, TPH2, HTR1A | NPC1 2072/4885POLB 4133/4885RAB9A 2533/4885 |
| US-20110190494-A1 | 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT | ASH2L, SETDB1, KAT5 | NPC1 4344/4885POLB 1855/4885RAB9A 4644/4885 |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | JUP, L1CAM, EPCAM | NPC1 3239/4885POLB 473/4885RAB9A 2248/4885 |
| US-20210193935-A1 | P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES | JUP, L1CAM, EPCAM | NPC1 3239/4885POLB 473/4885RAB9A 2248/4885 |
| US-20090066231-A1 | Electroluminescent device | CD99, TEC, TYR | NPC1 4682/4885POLB 3677/4885RAB9A 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.