Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BMP1 | P13497 | 2/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.45 |
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797683 | 0.76 | BMP1 (0.55) | CXCR3ALDH1A1BMP1TAS2R14KEAP1 | |
| SCHEMBL2582390 | 0.71 | BACE1 (0.52) | CXCR3MMP2MMP13ADAMTS4MMP14 | |
| SCHEMBL7004439 | 0.70 | MEN1 (0.52) | CXCR3ALDH1A1BMP1TAS2R14PTGES | |
| SCHEMBL9287153 | 0.70 | RORC (0.68) | CXCR3BMP1TAS2R14KEAP1PTGES | |
| SCHEMBL7956727 | 0.69 | CXCR3 (0.54) | CXCR3TP53 | |
| SCHEMBL7341408 | 0.69 | KEAP1 (0.67) | CXCR3BMP1TAS2R14KEAP1NFE2L2 | |
| SCHEMBL7341410 | 0.69 | KEAP1 (0.67) | CXCR3BMP1TAS2R14KEAP1NFE2L2 | |
| SCHEMBL14647093 | 0.69 | BACE1 (0.58) | CXCR3ALDH1A1BMP1TAS2R14KEAP1 | |
| SCHEMBL4797688 | 0.69 | TAS2R14 (0.59) | CXCR3BMP1TAS2R14KEAP1PTGES | |
| SCHEMBL8436783 | 0.69 | TP53 (0.64) | CXCR3ALDH1A1BMP1KEAP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |