Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL28321765 | 0.84 | QPCT (0.50) | QPCTQPCTLALDH1A1HPGDKDM4E | |
| SCHEMBL627763 | 0.82 | QPCT (0.62) | ESR2TRPA1QPCTQPCTLALDH1A1 | |
| SCHEMBL30799073 | 0.82 | TRPA1 (0.55) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL627762 | 0.82 | TRPA1 (0.55) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| Benzimidazole SCHEMBL9127791 | 0.79 | TSHR (0.56) | LRRK2QPCTQPCTLALDH1A1HPGD | |
| Biphenyl SCHEMBL14655620 | 0.79 | SMN1; SMN2 (0.48) | QPCTQPCTLALDH1A1HPGDKDM4E | |
| Benzimidazole SCHEMBL29037293 | 0.78 | TSHR (0.50) | QPCTQPCTLALDH1A1HPGDKDM4E | |
| Benzimidazole SCHEMBL1347288 | 0.77 | KDM4E (0.50) | QPCTQPCTLALDH1A1HPGDKDM4E | |
| Benzimidazole SCHEMBL2971795 | 0.77 | SMN1; SMN2 (0.48) | QPCTQPCTLALDH1A1HPGDKDM4E | |
| SCHEMBL223 | 0.77 | ESR2 (0.69) | ESR2GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143435-B2 | One pot process for the preparation of candesartan | Mylan Laboratories Ltd. (IN) | 2012-03-27 | — | — | US | disclosed |
| US-20110034701-A1 | ONE POT PROCESS FOR THE PREPARATION OF CANDESARTAN | MATRIX PHARMACORP PRIVATE LIMITED (IN) | 2011-02-10 | — | — | US | disclosed |
| WO-2008044244-A2 | ONE POT PROCESS FOR THE PREPARATION OF CANDESARTAN | MATRIX LABORATORIES LTD (IN) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034701-A1 | ONE POT PROCESS FOR THE PREPARATION OF CANDESARTAN | REN, AGTR1, GLP1R | ESR2 2334/4885GABRG2 1061/4885GABRB3 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.